Picornaviridae
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New Types

Proposals for the designation of RV-C types have been published (Simmonds et al., 2010; McIntyre et al., 2013).

Type Prototype strain CG acc. VP1 acc. VP4/VP2 acc. Reference/proposed by
HRV-C1  NAT001  EF077279* - - Kistler et al., 2007 
HRV-C2  NAT045  EF077280* - - Kistler et al., 2007 
HRV-C3  QPM  EF186077* - - McErlean et al., 2007 
HRV-C4  024 EF582385* - - Lau et al., 2007 
HRV-C5  025 EF582386* - - Lau et al., 2007 
HRV-C6  026 EF582387* - - Lau et al., 2007 
HRV-C7  NY-074  DQ875932* - - Lamson et al., 2006 
HRV-C8  N4  GQ223227* - - Huang et al., 2009 
HRV-C9  N10  GQ223228* - - Huang et al., 2009 
HRV-C10  QCE  GQ323774* - - Arden et al., 2010b 
HRV-C11  CL-170085  EU840952* - - Tapparel et al., 2009b 
HRV-C12  Resp_3922/07 n/a HM236958* EF077264 Kistler et al., 2007; McIntyre et al., 2010 
HRV-C13  Resp_2951/06 n/a HM236908* EU081795 Renwick et al., 2007; McIntyre et al., 2010 
HRV-C14  Resp_3090/06 n/a HM236911* EU081796 Renwick et al., 2007; McIntyre et al., 2010 
HRV-C15  Resp_4644/07 n/a HM236963* EU081800 Renwick et al., 2007; McIntyre et al., 2010 
  W10 (USA, 2007) GU219984 - - Bochkov et al., 2011
HRV-C16  Resp_5910/07 n/a HM236944* EU081808 Renwick et al., 2007; McIntyre et al., 2010 
HRV-C17  Resp_5145/07 n/a HM236936* EU081809 Renwick et al., 2007; McIntyre et al., 2010 
HRV-C18  Resp_3631/07 n/a HM236918* EU590074 Savolainen-Kopra et al., 2009a; McIntyre et al., 2010 
HRV-C19  CL-Fnp5 n/a EU840728*† EU697850 Briese et al., 2008; Tapparel et al., 2009a 
HRV-C20  Resp_3995/07 n/a HM236923* EU697851 Briese et al., 2008; McIntyre et al., 2010 
HRV-C21  Resp_5071/07 n/a HM236903* EU752377 Miller et al., 2009a; McIntyre et al., 2010 
HRV-C22  Resp_2748/06 n/a HM236905* EU752381 Miller et al., 2009a; McIntyre et al., 2010 
HRV-C23  Resp_3053/06 n/a HM236901* EU752424 Miller et al., 2009a; McIntyre et al., 2010 
HRV-C24  Resp_7147/07 n/a HM236939* EU752426 Miller et al., 2009a; McIntyre et al., 2010 
HRV-C25  Resp_2832/06 n/a HM236952* EU752427 Miller et al., 2009a; McIntyre et al., 2010 
  LZ269 JF317013 - - Yan et al., unpub.
HRV-C26  Resp_2514/06 n/a HM236904* EU752441 Miller et al., 2009a; McIntyre et al., 2010 
HRV-C27  Resp_2784/06 n/a HM236906* GQ223122 Huang et al., 2009; McIntyre et al., 2010 
HRV-C28  Resp_3105/06 n/a HM236954* GQ223134 Huang et al., 2009; McIntyre et al., 2010 
HRV-C29  Resp_5345/07 n/a HM236949* FJ615699 Miller et al., 2009b; McIntyre et al., 2010 
HRV-C30  Resp_3898/07 n/a HM236968* GQ476669 Wisdom et al., 2009b; McIntyre et al., 2010 
HRV-C31  Resp_4923/07 n/a HM236964* GU294380 Wisdom et al., 2009b; McIntyre et al., 2010 
HRV-C32  Resp_6131/07 n/a HM236897* GU294466 Wisdom et al., 2009b; McIntyre et al., 2010 
HRV-C33  Resp_4917/07 n/a HM236934* GU294480 Wisdom et al., 2009b; McIntyre et al., 2010 
HRV-C34 pico58
PNG7111-3625		 awaited
n/a		 -
 JF519758		 -
 JF519759		 Michael Lindberg, pc 2010
Glenys Chidlow, 2012
HRV-C35 LRTI-metagen.-1
06-739b		 JF436925
n/a		 -
n/a		 -
 EU081790		 Lysholm et al., 2012
Renwick et al., 2007
HRV-C36 NAT069
Resp_2480/07
Resp_3137/07
Resp_3451/07
Resp_3832/07		 n/a
n/a
n/a
n/a
n/a		 n/a
JF416311
JF416314
JF416316
JF416317		 EF077256
?
?
?
?		 Kistler et al., 2007 
McIntyre et al., pc 2011
McIntyre et al., pc 2011
McIntyre et al., pc 2011
McIntyre et al., pc 2011
HRV-C37 NAT059
Resp_6135/08		 n/a
n/a		 n/a
JF416321		 EF077260
GU294476		 Kistler et al., 2007
McIntyre et al., pc 2011; Wisdom et al., 2009
HRV-C38 tu304
Resp_6142/08		 n/a
n/a		 n/a
JF416322		 EU081791
GU294477		 Renwick et al., 2007
McIntyre et al., pc 2011; Wisdom et al., 2009
HRV-C39 g2-11
Resp_10221/08		 n/a
n/a		 n/a
JF416306		 EU081799
?		 Renwick et al., 2007
McIntyre et al., pc 2011
  WA823M02 JN205461 - - Chidlow et al., unpublished
HRV-C40 g2-25
Resp_2800/06
Resp_3091/07
Resp_3373/07		 n/a
n/a
n/a
n/a		 n/a
JF416312
JF416313
JF416315		 EU081802
?
?
?		 Renwick et al., 2007
McIntyre et al., pc 2011
McIntyre et al., pc 2011
McIntyre et al., pc 2011
HRV-C41 g2-23
Resp_9449/08
Resp_10061/08
2536/USA/2000		 n/a
n/a
n/a
KF958311		 n/a
JF416323
JF416305
-		 EU081803
?
?
-		 Renwick et al., 2007
McIntyre et al., pc 2011
McIntyre et al., pc 2011
Nakagome et al., 2014
HRV-C42 g2-28
Resp_5477/08		 n/a
n/a		 n/a
JF416320		 EU081805
?		 Renwick et al., 2007
McIntyre et al., pc 2011
HRV-C43 06-230
Resp_13229/08
Resp_14458/08		 n/a
n/a
n/a		 n/a
JF416307
JF416309		 EU081807
?
?		 Renwick et al., 2007
McIntyre et al., pc 2011
McIntyre et al., pc 2011
HRV-C44 PNC40168
Resp_15588/09		 n/a
n/a		 n/a
JF416310		 EU590061
?		 Savolainen-Kopra et al., 2009a
McIntyre et al., pc 2011
HRV-C45 PNC40449
Resp_13958/08		 n/a
n/a		 n/a
JF416308		 EU590064
?		 Savolainen-Kopra et al., 2009a
McIntyre et al., pc 2011
HRV-C46 KR2315
Resp_5153/07
Resp_5154/07		 n/a
n/a
n/a		 n/a
JF416318 JF416319		 FJ869950
GU294446
GU294447		 Calvo et al., 2009
McIntyre et al., pc 2011.; Wisdom et al., 2009
McIntyre et al., pc 2011; Wisdom et al., 2009
HRV-C47 K1091 301104
PNG7254-3947		 n/a
n/a		 n/a
JF519760		 GQ466482
JF519761		 Savolainen-Kopra et al., 2009c
Chidlow et al., 2012
HRV-C48 PNG7293-3193 n/a JF519762 JF519763 Chidlow et al., 2012
HRV-C49 WA1104OM
IN-36		 n/a
n/a		 JF946738
n/a		 JF946737
EU697839		 Glenys Chidlow, pc 2011
Briese et al., 2008 
HRV-C50 SG1/AUS/2008
SO5986
PUMCH1601
LZY242		 KF688606
n/a
n/a
n/a		 JQ739202
n/a
n/a
n/a		 -
FJ841957
FJ950847
JF316873		 Mackay et al., unpub.
Calvo et al., 2009
Xiang et al., 2010
Yan et al., unpub.
HRV-C51‡ LZ508/China/2007
JAL-1/USA/2010
HRV-CO-1368		 JF317015
JX291115
n/a		 -
-
-		 -
-
EU743925		 Yan et al., unpub.
J.A. Lednicky & J.C. Loeb, unpub.
Dominguez et al., 2008
HRV-C52 D1880-V1 - KP736724 KP737058 Zlateva et al., unpublished
HRV-C53 H1380-V1 - KP736726 KP736993 Zlateva et al., unpublished
HRV-C54 D3490/SPA/2009 KP282614 - - Jazaeri Farsani et al., 2015
HRV-C55 529T n/a KR997885 KR997885 L'Huillier et al., 2015
HRV-C56 JPN/Kumamoto1/2009 n/a LC004772 n/a Kuroda et al., 2015
HRV-C57 7383-MY-10 KP890662 - - Khaw et al., 2016 / proposed by Ian Mackay
           

The proposal for the designation of HRV-C types 1-33 has been published (Simmonds et al., 2010). New types are assigned if they have more than 13% nucleotide difference in VP1 to all the prototype viruses. Provisional types may be designated if no VP1 sequence is available and there is more that 10% nt difference in the VP4/VP2 region (395 nt starting at the beginning of VP4) to the prototype viruses.

*, sequence of prototype strain
†, complete P1 sequence
‡, LZ508 is closely related to HRV-CO-1368 (formerly HRV-C_pat15) in the VP2/VP4 region, but JAL-1 is very different to both.

Provisionally assigned human rhinovirus C types (based only on VP4/VP2 sequences)

References

McIntyre, C.L., Knowles, N.J. and Simmonds, P. (2013). Proposals for the classification of human rhinovirus species A, B and C into genotypically assigned types. J. Gen. Virol. 94: 1791-1806.

Simmonds, P., McIntyre, C.L., Savolainen-Kopra, C., Tapparel, C., Mackay, I.M. and Hovi, T. (2010). Proposals for the classification of human rhinovirus species C into genotypically-assigned types. J. Gen. Virol. 91: 2409–2419. [Epub 2010 Jul 7]